Now, this bearded band goes back to Fenway Park just one win away.
"Pretty special time," Lester said.
Lester bested Adam Wainwright once again, journeyman David Ross hit a tiebreaking double in the seventh inning and the Red Sox downed the St. Louis Cardinals 3-1 on Monday night to take a 3-2 Series edge.
David Ortiz delivered his latest big hit, too, putting Boston in position to capture its third crown in a decade. Not since 1918 have the Red Sox clinched the title at their century-old bandbox.
"The fact is we're going home," manager John Farrell said. "Going back to a place that our guys love to play in, in front of our fans.
"This atmosphere here, these three games, has been phenomenal. We know it's going to be equal to that, if not better. And we're excited about going home in the position we are."
Said Ortiz: "It's going to get loud out there."
John Lackey gets the first chance to win it Wednesday night against St. Louis rookie sensation Michael Wacha. A Cardinals victory would set up a most spooky proposition for both teams -- Game 7 on Halloween night.
"It will be legendary if we go into Boston and win two games," Wainwright said.
Ortiz enjoyed even more success in Game 5 after moving up from cleanup to the third slot. He is 11-for-15 (.733) in the series with two homers, six RBIs and four walks.
"I was born for this," Ortiz said, grinning.
He left in a double switch, shortly after legging out a single in the eighth. He was OK, and he already had done enough damage to the Cardinals.
"What planet's that guy from?" Ross said.
Lester enhanced his reputation as an October ace with every pitch. He allowed one run and four hits in 7 2/3 innings, striking out seven without a walk. It was nearly the same line he had in beating Wainwright in the opener.
"I think the biggest thing is me and Rossy have had a good rhythm," Lester said of his primary catcher. "Early on, we just went back to our game plan from Game 1 and just fell back on that and really just tried to make them swing the bats early, and we were able to do that."
The lefty, who has won all three of his career World Series starts, had just one rough inning, when Matt Holliday homered in the fourth, Carlos Beltran flied out to the wall and Yadier Molina hit a liner. Other than that, Lester was as sharp as a knife and at one point retired 12 in a row.
He tweaked himself late but said he was all right. In fact, Lester's biggest brush with major trouble came well before his first pitch.
Lester was getting loose near the warning track when a team of eight Clydesdales pulling a beer wagon came trotting by. He moved aside to watch the Busch Stadium tradition.
He also took a brief break in the seventh. A giant paper airplane floated down from the stands, and some fans cheered its flight as it landed near the mound. Lester handed it to a ball boy, then got Molina to line out to shortstop to end the inning.
"It was a tough loss. It was 1-1 in the seventh -- that was obviously the game. Tip your cap to Ross; he hit a double to take the lead," Wainwright said. "Their guy Lester did a good job."
Lester did it without any flap over his glove. During Game 1, a Cardinals minor league pitcher posted a picture on Twitter of discoloration on Lester's mitt and wondered whether some foreign substance was there.
Lester said he merely used rosin for a better grip, and Major League Baseball said it didn't see anything wrong.
Koji Uehara got four outs for his second save of the series. No crazy endings this time, either, following one night with an obstruction call and the next with Uehara's game-finishing pickoff.
The Cardinals went quickly in the ninth and now need two wins in Boston. They overcame a 3-2 series deficit at home to beat the Texas Rangers for the 2011 title.
"The guys know what we have to do," manager Mike Matheny said. "We have to play the game. They have to lock arms, trust each other and play the game the right way. Most of it is going to be the mentality of not buying into any kind of stats, any kind of predictions, any kind of odds, and go out and play the game."
Ortiz put Boston ahead with an RBI double in the first, hitting the first pitch after Dustin Pedroia doubled on an 0-2 curve. Ortiz singled the next time up and tied a World Series record by reaching base in nine straight plate appearances.
"Big Papi" and the Red Sox took two of three at the National League park despite playing without a designated hitter. Ortiz became the first baseman, putting slugger Mike Napoli on the bench.
The Red Sox lead the series despite a .205 team batting average. Ortiz has one-third of the team's 33 hits.
Ross, a graybeard on a team led by scraggly veterans, broke a 1-1 tie when he hooked a drive just inside the left-field line, and the ball bounced into the seats for a go-ahead double.
"How about that? It's nice to drive in runs," Ross said. "I've got to credit the guys in front of me."
Jacoby Ellsbury later hit an RBI single, and Ross was thrown out at the plate trying to score on the play.
A day after Ortiz delivered a stirring, in-game pep talk to rev up the Red Sox, the Cardinals could have used some inspiration themselves -- perhaps a visit from the good-luck "rally squirrel" from their 2011 title run.
The St. Louis hitters went quietly, a couple slinging their bats after routine popups and fly balls, and others questioning the calls by plate umpire Bill Miller.
Holliday shook St. Louis' slumber and broke Lester's string with his second home run of the series. Lester had pitched 16 1/3 scoreless innings in his first three World Series starts before Holliday tagged him.
That was all St. Louis got. Not even a revamped lineup that included the hobbled Allen Craig helped the Cards.
Craig, who is still suffering the effects of stretched ligaments in his left foot, was a late replacement for first baseman Matt Adams on Monday. Craig had been batting .444 (4-for-9) in the series but was hitless in three at-bats in Game 5. He and Matheny told MLB.com after the game that he likely will return to designated hitter when the series returns to Boston.
"It just continues to improve, and I can get better," Craig told the website.
Wainwright changed things the next time Ortiz came up, varying his tempo and delivery. Ortiz still hit it hard while lining out to center.
Wainwright struck out 10 in seven innings, becoming the first Cardinals pitcher to reach double digits in a World Series game since Bob Gibson did it twice in 1968 against the Detroit Tigers.
It was a big sports night in St. Louis, with a "Monday Night Football" game between the St. Louis Rams and Seattle Seahawks eight blocks away at the Edward Jones Dome. This is a baseball town, clearly: Football tickets sold for $10 on StubHub as kickoff approached, and fans inside the dome loudly booed when the World Series game was taken off the video board.
The baseball fans got to see Lester do more than pitch. He helped himself in the field, knocking down a hard comebacker and swiftly handling a bunt. He also made a dent with his bat, sort of.
Going in with a career 0-for-31 mark at the plate, he nubbed a ball in front of the plate and was thrown out leading off the third. But at least he broke Wainwright's string of five straight strikeouts, one shy of the postseason record tied by Detroit's Justin Verlander against Boston in the American League Championship Series.
The Red Sox struck out 14 times, raising their total to a postseason-record 156. Boston came in with with 142, tied with the 2010 champion San Francisco Giants. ... RF Shane Victorino was again out of the Red Sox lineup because of lower back stiffness. ... Wacha is 4-0 with a 1.00 ERA in four postseason starts, including a win in Game 2.
The Associated Press and ESPNBoston.com's Gordon Edes contributed to this report.