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CHICAGO -- No. 9 hitter Robert Andino supplied some power, aggressive baserunning and a great play at shortstop to help the Baltimore Orioles send the Chicago White Sox to yet another defeat.

Andino's antics were pivotal in the Orioles' 6-2 victory Saturday night, but manager Buck Showalter pointed to the work of reliever Mike Gonzalez as the key.

The hard-throwing lefty pitched out of a bases-loaded, no-out jam with only one run scoring in the sixth. He struck out Adam Dunn and A.J. Pierzynski to stop a potential big inning by the struggling White Sox, who've lost 14 of 17.

"Gonzalez was the star," Showalter said. "Big momentum swing with Dunn coming up there. I said, 'Let it loose, let it hang out, let's go.'

"He's always emotionally into it. Nobody is a robot that doesn't have emotions. Everybody pulls for him. [The offense] fed off his success as much as he did."

Leading 2-1, the Orioles tacked on four runs in the eighth, an inning featuring a passed ball and error on Chicago catcher Pierzynski, some daring baserunning by Andino and a two-run single by Vladimir Guerrero.

White Sox manager Ozzie Guillen missed the game, completing his two-game suspension for tweeting comments about an umpire after he was ejected three nights earlier in New York. Bench coach Joey Cora ran the team for the second straight game.

With or without their manager, the White Sox can't win and finished April 10-18 -- the most losses in April in franchise history. They've dropped four straight.

"The league is not going to be feeling sorry for us or wait for us or nothing. We are going to have to play and play through it and start winning some ballgames," Cora said.

Baltimore's Chris Tillman (1-2), who had to skip his previously scheduled start because of a sore groin, had a 2-0 lead and was pitching well into the sixth when he gave up singles to Alexei Ramirez and Carlos Quentin and walked Paul Konerko to load the bases with no outs.

Showalter went to the bullpen for Gonzalez, who struck out Dunn looking. Alex Rios then hit a fly ball to medium center field and Adam Jones made a strong throw to the plate that appeared to be in time to get Ramirez, but Orioles catcher Jake Fox couldn't hold the throw, making it 2-1. Gonzalez then fanned Pierzynski to end the threat.

Phil Humber (2-3), who took a no-hitter into the seventh inning in his previous start against the Yankees, had another solid outing, giving up three hits and two runs in seven innings.

"Our job is to go out there and go deep in the ballgame and keep us close and give our offense a chance," Humber said. "Right now we're not scoring a whole lot of runs, but I think that is going to turn around, I really do. I've got all the faith in the world in these guys. ... Hopefully it turns around for us pretty quick."

Andino led off the third with his first homer of the season -- and seventh in parts of seven major league seasons -- to put Baltimore up 2-0. The Orioles took an early lead when Brian Roberts doubled to lead off the game, went to third on a fly ball and scored on Humber's wild pitch, a low delivery that eluded Pierzynski.

"I wish I could take one pitch back, the one to Andino," Humber said. "Other than that pitch and not being there to cover home in the first inning that kind of bit us there. Other than that I threw the ball pretty well."

Andino also blunted a Chicago rally in the fourth when the White Sox had first and second and no outs. He made a diving stop on Rios' grounder behind the bag and started a double play with a nice flip to Roberts.

"He's been playing good shortstop," Showalter said.

Andino singled in the eighth off Matt Thornton and stole second. When Roberts struck out, the ball got by Pierzynski, who retrieved it and threw low to Dunn at first. Dunn caught the one-hop throw but his relay to the plate was too late to get Andino, who scored all the way from second.

"I came around third aggressive," Andino said. "He might throw the ball. In this game, anything happens. ... Once I saw the ball hit the dirt, I made up my mind."

Nick Markakis followed with a single and Derrek Lee walked to load the bases before Guerrero delivered a two-run single past third. Luke Scott's sacrifice fly made it 6-1 and Thornton was booed as he left the mound.

Rios hit his first homer of the season in the ninth to make it 6-2.

Game notes

The Orioles have won four of their past five. ... Guillen said he watched Friday night's 10-4 loss on TV. He said that was more difficult than from the dugout because he has to watch replays and can still hear the booing. He said he was in the parking lot and then went home Friday night. "It was painful to watch as a fan," he said. ... Dunn, who underwent an appendectomy and was 7-for-61 over his previous 17 games, got his first start at first base for the White Sox after serving for 20 games as a DH. He went 1-for-4 Saturday night. ... RHP Jake Peavy (shoulder) is scheduled to make his next rehab start on May 5 for the White Sox's Triple-A Charlotte team and throw 100 pitches. ... Orioles' DL update: SS J.J. Hardy (left oblique) hit off a tee, ran the bases and took ground balls Saturday. RHP Justin Duchscherer (left hip) threw 30 pitches in batting practice and said he felt great afterward. LHP Brian Matusz (back) threw 45 pitches in a side session Saturday and reported no problems.