SAN DIEGO -- The Milwaukee Brewers' domination of the NL West could go a long way in helping them win the NL Central.
Milwaukee has won 10 of 11 games on the road against NL West opponents this season. The Brewers' .910 winning percentage against the NL West is the highest road winning percentage by any team against any single division this season.
Lohse (12-7) allowed a run and four hits over six innings in making his first start since spraining his right ankle Aug. 13. He beat the Padres for the fourth straight time.
"The ankle was fine," Lohse said. "It was one of those things where I felt really good and really strong. And we kept putting up runs. ... I'm not used to having almost two weeks off late in the season. Everything else has been feeling good but I just needed a little break to get ahead of the ankle soreness."
Eric Stults (6-14) was charged with four runs and nine hits in five innings as he lost his first game in August to snap his three-game winning streak.
"We did a really good job offensively today," Brewers manager Ron Roenicke said. "Everybody seemed to chip in, and that is always nice to see."
Lohse skipped his last turn in the rotation after getting hurt against the Cubs. But he was efficient in striking out five as the Brewers stayed 1 1/2 games ahead of the St. Louis Cardinals in the NL Central.
When he struggled early with his fastball, he turned to his off-speed pitches in stifling the Padres.
"He looked like he settled down and got things working," Roenicke said. "He had a good changeup, real good curveballs, nice sliders. I was happy to see him get back into that rhythm again."
Ramirez's 14th home run came in the fifth inning off an 87 mph fastball from Stults and extended Milwaukee's edge to 4-1.
The Brewers broke the game open with a three-run sixth en route to their fifth straight road win.
Braun's 17th home run, in the third inning, gave the Brewers a 2-1 lead, when he hit it into the left-center seats. Martin Maldonado added a run-scoring single for a 3-1 advantage.
"They were on tonight and they are an aggressive group," Padres manager Bud Black said. "They have power, they don't walk much or strike out much. It's a good offensive group."
Braun was lifted for Parra in the seventh inning with a left quadriceps contusion suffered in a first-inning collision with Padres first baseman Jake Goebbert, but he is expected to play Tuesday.
"I'm OK," Braun said, according to the Milwaukee Journal Sentinel. "I didn't want to come out; I was OK. Just a little banged up. It was pretty painful knee-to-knee contact. It didn't feel good for me and I know it didn't feel good for him, either. It was kind of one of those fluke plays that happens from time to time."
The Padres tied the game 1-all in the second but the Brewers got off easy.
Will Venable then struck out to end the inning, stranding two runners.
The Padres have lost eight of their past 11 games.
Padres: OF Carlos Quentin isn't going to play again the season, according to manager Bud Black. Quentin was limited to 50 games because of sore knees, with his most recent DL stint starting July 27. ... Second baseman Jedd Gyorko, who strained his left hamstring Thursday, returned to action by grounding out as a pinch hitter. ... SS Everth Cabrera (strained left hamstring) has resumed baseball activities but is probably out another week.
Brewers: RHP Matt Garza, on the disabled list with a strained left oblique, will have another bullpen session Tuesday. If it goes well, he could rejoin the rotation.
Brewers: RHP Jimmy Nelson (2-4, 4.15 ERA), who lost in his last start against the Blue Jays on Wednesday, will be looking to rebound against the Padres.
Padres: RHP Tyson Ross (11-12, 2.68) has worked at least six innings in 21 of his past 25 starts, including seven or more in 13 of those outings. His 12 straight quality starts is a franchise record.
Dick Enberg, the Padres' TV play-by-play announcer, is headed for the US Open. Enberg, CBS' longtime voice at the Open, will return to call one last match Sunday. With TV coverage switching to ESPN next year, CBS invited Enberg back to show its appreciation for his contributions. Enberg will miss the Padres' weekend series against the visiting Los Angeles Dodgers.
FIRST THINGS FIRST
The Brewers have had at least a share of first place in the NL Central every day since April 5, a span of 143 days. Milwaukee last won a division title in 2011.
The Associated Press contributed to this report.