Both clubs know this division race is far from over, with five meetings remaining before August ends and another three in late September. And with a margin of error so slim, one miscue might be the difference.
Luke Gregerson (3-2) pitched a perfect eighth, and Doolittle finished for his 20th save. The closer felt something in his right side nearer to his back, but was able to go through some twisting exercises and other postgame tests with no problem. He doesn't consider it serious.
The division co-leaders (76-52) have the most wins in baseball. The Angels lost their fifth straight game this season at O.co Coliseum.
On Monday in Boston, the Angels moved into sole possession of the division's top spot for the first time since May 15, 2011. Losing the first two games of this series has things all tied up again.
Lester struck out seven in seven innings, including Mike Trout three times as the slugger's five-game home run streak at the Coliseum was snapped.
Lester bounced back from his first defeat in nearly 2½ months and first since joining the A's from Boston at the trade deadline. The lefty threw a combined 18 pitches in the fifth and sixth innings, 14 for strikes. He then allowed three straight hits in the seventh, including a double by Howie Kendrick and Erick Aybar's RBI single that made it 1-1.
The A's have struck out Trout three or more times in one game six times for his career, most by any team.
"Maybe we were able to get him off his game a little bit, get him frustrated and to swing at bad pitches," Lester said.
Lester was helped by a nice play from left fielder Craig Gentry in the seventh. David Freese hit a leadoff single off the wall and headed toward second as Gentry quickly retrieved the ball and threw him out.
Wilson allowed one run on five hits, struck out three and walked three in 6⅓ innings.
"The A's do a lot of things well. They pitch well and they have a good bullpen. It was another close game and we didn't get a couple of things done," Angels manager Mike Scioscia said. "We have to keep moving forward."
Scioscia challenged in the third that Albert Pujols beat out an infield hit rather than recording the third out. The call was overturned in 2 minutes, 4 seconds, and ruled a single.
In the sixth, umpires went to review again on a challenge by A's manager Bob Melvin. He believed Josh Donaldson, who held up briefly at second, was safe at home on a headfirst slide in which he reached to touch the plate with his left hand as catcher Chris Iannetta tried to tag him. The ruling stood after 3:40.
The crew chief then reviewed Sam Fuld's caught stealing in the seventh, per Melvin's request. The ruling was confirmed in 1:05.
Los Angeles 3B Gordon Beckham joined his new team, two days after being acquired by the Angels from the White Sox for a player to be named or cash. He earned a start and batted ninth, going 0-for-3 with a pair of called third strikes.
"Gordon will help in a lot of ways," Scioscia said. "Hopefully he'll give us depth at some key positions."
The Angels optioned RHP Cam Bedrosian to Triple-A Salt Lake.
Athletics: More should be known about Doolittle's status Sunday. ... An MRI exam revealed 1B Kyle Blanks has tendinitis in his left Achilles tendon. He had pain in both feet and his lower legs while on a rehab assignment. "He's going to be shut down for a while," Melvin said.
Angels: The series has shifted game times from 7:05 p.m. to 6:05 and now 5:05 for the series finale. RHP Jered Weaver (13-7, 3.70 ERA) tries again for his first win of 2014 against the A's, going 0-2 with a 7.15 ERA in his first two outings.
Athletics: LHP Scott Kazmir (14-5, 2.73) starts the finale. The A's expect to call up Drew Pomeranz to start Wednesday at Houston and push Friday winner Sonny Gray to Thursday to keep this weekend's rotation the same for a four-game road series next week with the Angels.