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Tigers strike first in Seattle

Tigers 3B Nick Castellanos hit his 5th HR of the year to left off Hisashi Iwakuma to put the Tigers up 1-0 in the 2nd. Follow live

Reds snap 3-game slide in opener

Eugenio Suarez's go-ahead solo shot in the eighth stood as the difference in the Reds' 3-2 win over the Nationals in D.C. Suarez finished 3-for-4 with 2 RBIs. Box score

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Astros add a half game to AL West lead

The Astros posted a four-run first and rolled to a 9-4 win over the Indians in their opener. Houston snapped a two-game skid, while sending Cleveland to a third straight defeat. Box score

AP

Pedro Alvarez delivers walk-off single

A.J. Burnett limited the Padres to one run over 7 2/3 innings, and the Pirates' bats did the rest, coming through with a walk-off hit in the ninth to win their third straight, 2-1, in the series opener. Box score

Getty

Cardinals-Cubs in rain delay

Rain finally delayed this game at Wrigley Field with St. Louis leading 2-0 in the middle of the 8th. Chicago LHP Jon Lester took a no-hit bid into the 7th, but the Cards' offense finally got to him. If the game is called, John Lackey would get the win.

Getty

Sale goes distance to quiet Blue Jays

All-Star Chris Sale struck out 6, ending his run of 8 straight games with at least 10 K's, but allowed just 2 runs over 9 innings. The White Sox gave him the necessary run support with 3 unearned runs off Mark Buehrle in the 8th, capped by a 2-run double from Melky Cabrera.

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Watch: Quick turn of events in Chicago

Jon Lester went into the 7th with a no-hitter, and now he's down 2-0 thanks to a Yadier Molina RBI sac fly and a Kolten Wong RBI single as the rain still falls at Wrigley. Live on ESPN/WatchESPN

#VoteAltuve @astros

A sac fly cuts the #Astros' lead to 9-4 game but Neshek gets a ground ball to retire the side. We head to the 8th inning in Cleveland.

Watch: Jon Lester gives up hit in 7th

The Cardinals got their first hit from All-Star Jhonny Peralta's solid one-hopper to fellow All-Star Kris Bryant, who couldn't handle it. It's 0-0 in the 7th, but the Cardinals are threatening. Live on ESPN/WatchESPN

Jayson Stark @jaysonst

Ned Yost only had option to add 2 position players, plus Teixeira as replacement for Miggy. Took Martin as 3rd C & Holt as only #Redsox rep

ESPN Stats & Info @ESPNStatsInfo

Cubs pitcher hasn't thrown a no-hitter at Wrigley Field since 1972 (Milt Pappas). Jon Lester takes his bid into 7th inning vs STL (ESPN)

Watch: Cubs miss huge chance

All-Stars Anthony Rizzo and Kris Bryant started off the bottom of the 6th with back-to-back singles off Cards RHP John Lackey, but after Miguel Montero struck out, Starlin Castro hit into a DP to end the inning. It's scoreless through 6. Live on ESPN/WatchESPN

Sale likely not reaching double-digit K's

White Sox SP Chris Sale has struck out 5 batters through 8 IP and is trailing 2-1 to the Blue Jays after giving up homers to Chris Colabello and Josh Donaldson. He'll need a lot of help if he's to get his record 9th straight game with at least 10 K's. Follow live

Reds @Reds

Manny Parra tosses a 1-2-3 inning. We'll head to the 8th inning in DC all knotted up at 2. Pena will lead it off for the #Reds