The distraction stemming from the trade was evident on the court, especially during a woeful second half.
"When word got around, guys kind of lost their concentration," Washington coach Flip Saunders said.
Philadelphia, which has won 11 of 15, improved to 18-9 at home.
"It was a big win for us," Brand said. "We're playing with a whole lot of confidence now."
Washington (15-41), one of the worst teams in the league, has lost three straight. With its season long gone, it made a trade during the game to stock up for the future.
"It was a pretty tough thing to hear," Wall said. "Kirk's a veteran guy who taught me an awful lot about NBA basketball. I'll really miss him. And Hilton was a good friend, too. I wish them both well."
Hinrich and Armstrong were on the bench for the whole first half, but never came out of the locker room after halftime.
"I think when the deadline is over, guys will have a sense of relief," Saunders said.
Meanwhile, Iguodala has been linked to a number of trade scenarios in recent weeks. The trade deadline is 3 p.m. ET on Thursday.
"I like our team," Sixers president Rod Thorn said before the game. "Does that mean we wouldn't do something if the opportunity presented itself? No, we'll look at everything."
Philadelphia carried a 54-49 lead into halftime and grabbed control in the third quarter. Young's thunderous dunk with 3:50 left gave the Sixers a 78-60 lead.
Iguodala hit a 3-pointer during a 7-2 surge that gave Philadelphia a 95-66 lead in the fourth.
"I think it was a great thing to see us push forward in the second half," Young said. "We've had too many games this season where we let teams back in it. We didn't do that this time and I think it's a sign of us maturing as a team."
The Sixers are 25-16 since starting the season 3-13. ... Pennsylvania Gov. Ed Rendell attended the game. ... The Wizards fell to 1-27 on the road. ... Speights hit a 3-pointer in the fourth quarter, his first of the season. He had been 0 for 3. ... Booker scored 17 points in the fourth.