Ray Allen, making Miami debut, had 10 points and five assists in 27 minutes.
Wade is expected to travel with the Heat for a seven-day trip to China that will include exhibition games against the Los Angeles Clippers on Thursday and next Sunday.
James had six rebounds and a game-high six assists in 24 minutes.
After initially saying he was going to retire, Cavs forward Richard Jefferson told TMZ this week that he is "going to play a couple of more years."
Tom Penn breaks down what the Spurs would need to do to make enough cap space to sign Kevin Durant.
Michael C. Wright breaks down the chances Tim Duncan returns for his 20th NBA season.