Steve Nash added eight points and six assists in 28 minutes for the Lakers. All three did not play in the fourth quarter.
The Lakers' Dwight Howard will try to play Sunday night against Sacramento in Los Angeles. It will be determined by the Lakers medical staff. Howard, who had back surgery last April, made the trip to Las Vegas.
Devin Ebanks came off the bench with 20 points for Los Angeles, which played its annual preseason game at the Thomas & Mack Center. Ebanks was 4 of 5 from 3-point range.
The Kings were 22 of 27 (82 percent) from the free throw line and had a 28-10 advantage in fast-break points.
Bryant finished 7 of 12 from the field and 8 of 11 from the free throw line.