It was the second straight win for the Magic, who have two exhibition games remaining. The Spurs lost consecutive games for the first time this preseason and host Washington Friday in their final regular-season tune-up.
After playing sparingly in the Spurs' first four preseason games, Ginobili and Tony Parker played extended minutes for the second straight game.
Magic guard Arron Afflalo sat out again Sunday resting a sore left hamstring, but could make his preseason debut Wednesday against Memphis.
J.R. Smith drains a 3-pointer from deep in the first quarter against the Raptors.
Bismack Biyombo drains a jumper early in the first quarter against the Cavs.
Minnesota Timberwolves point guard Ricky Rubio's mother has died after a long battle with lung cancer.