Williams scored 13 points and Pekovic added 10 during an opening burst that gave the Timberwolves a 27-10 lead in the first quarter. Minnesota pushed its lead to 52-29 at the half.
The Pistons showed some life after the break, going on an 8-0 run to close the gap to five. Stuckey scored 13 third-quarter points after putting in eight in the opening half.
The Timberwolves bounced back to stretch their lead to 68-53 entering the fourth and were in control throughout the final quarter.
Check out top NBA playoff moments from the past week, including the Toronto Raptors' victory over the Cleveland Cavaliers to tie their series 2-2 and the Oklahoma City Thunder's victory to claim a 3-1 lead in their series with the Golden State Warriors.
The Jump crew examines Steph Curry's game and wonder if the MVP is hiding something or if his game is hurt.
The Chicago Sun-Times reports Joakim Noah has been telling teammates he is ready to leave Chicago, while a league source stressed to ESPN that a "positive dialogue" between the parties continues.