The win was Colorado's third straight and clinched the No. 8 seed in the Big 12 Tournament, where it will face No. 9 Texas Tech again on Wednesday. It marked Colorado's first three-game conference winning streak in seven years.
The Buffaloes (15-15, 6-10) used a 17-2 run early in the first half to blow open a close game. Led by Marcus Relphorde's 15 points, Colorado shot 59 percent in the first 20 minutes and led 53-35 at the break.
The Red Raiders (16-14, 4-12) trailed by double digits until Okorie's 3-pointer made it 88-79. Texas Tech got within eight in the final minutes but didn't get any closer.
Mike Brey is looking at former Notre Dame players to fill two assistant jobs that have opened up with the departures of Martin Ingelsby and Anthony Solomon.
Purdue's 2016-17 prospects got a jolt Wednesday when forward Caleb Swanigan announced he will return for his sophomore season.
Clemson's Jaron Blossomgame says he is withdrawing from the NBA draft and returning to school for a final season.