The Monarchs (7-2) started the game with an 18-0 run and maintained a double-digit lead the rest of the way.
The Hawks (2-6) did not make their first basket until a Lyvann Obame Obame layup with 12:36 to go in the first half.
Old Dominion outrebounded the Hawks 64-28, setting a Ted Constant Center record for most rebounds, and scored 24 second-chance points.
Keyon Carter added 13 points and nine rebounds for the Monarchs and Chris Cooper tied the arena record with a career-high 16 rebounds. Old Dominion's Alex Loughton also had 16 against George Mason in 2004.
Obame Obame and Dishawn Bradshaw scored eight points each for Maryland-Eastern Shore, which shot only 25.9 percent from the field (15 of 58).
The family of former Houston Astros owner Roy Hofheinz wants a court to require the University of Houston to keep his name on the school's basketball arena.
Michigan has hired assistant basketball coaches Billy Donlon and Saddi Washington.
Duke and Cincinnati, 2016 NCAA tournament teams, highlight the eight-team field for the Naismith Memorial Basketball Hall of Fame Tip-Off Tournament.
|South Carolina State||12-4||1||19-15|
|North Carolina Central||7-9||6||13-19|
|North Carolina A&T||7-9||6||10-22|
|Texas San Antonio||3-15||13||5-27|