The Spiders (22-7, 11-3 Atlantic 10) strengthened their hold on third place in the league and won for the sixth time in their last seven games.
Richmond pulled out to a 34-24 halftime lead, then turned back a Charlotte (10-18, 2-12) rally in the second half. The 49ers got as close as three points twice, the latest at 55-52 with 8:12 left, but the Spiders closed with a 17-7 surge the rest of the way.
Harper was 8 of 14 from the field with three 3-pointers, and had a team-high seven rebounds.
Anderson scored 12 of his 20 in the second half. His fastbreak layup with 7:35 remaining allowed him to surpass 2,000 points for his career.
The Spiders also got 11 points off the bench from Francis Martel.
The Kentucky coach is using this offseason to improve his physical condition.
Chattanooga men's basketball coach Matt McCall has received a two-year contract extension after leading the Mocs to an NCAA tournament appearance in his debut season.
North Carolina men's basketball coach Roy Williams joins Seth Greenberg for Fast Break to discuss his favorite pregame meal, how he picks his game-day outfit and what CDs (gasp!) he has in his car.
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