Anton Grady added 11 points for the Vikings (8-1, 2-0 Horizon), who won their third in a row. Six victories have come on the road.
Cleveland State was outshot, hitting 44.4 percent (24 of 54) to Detroit's 46.5 percent (20 of 43). But the Vikings held a 32-23 rebounding advantage, and the Titans made only 1 of 13 3-pointers.
Cleveland State got off to an 8-0 edge but did not take the lead for good until Charlie Lee sank two free throws to break a 24-24 with 5:57 left in the first half. The Vikings' largest lead with 14 in the second half.
Colorado State graduate transfer John Gillon has chosen Syracuse, giving the Orange a potential starter at point guard entering the 2016-17 season.
DeSean Murray, who averaged 20.2 points as a sophomore at Presbyterian, will transfer to Auburn to play for coach Bruce Pearl.
Former Kentucky guard Ed Davender, the only Wildcat with at least 1,500 points and 400 assists, has died. He was 49.