Anderson also was a big factor on the boards and on defense, coming up with nine rebounds and five steals.
McCallum's effort included six assists and five rebounds.
Detroit also was effective from 3-point range, converting 11 shots from beyond the arc.
Northern Michigan's shooting touch was off most of the night, hitting just a third of its shots from the field.
T.J. Cameron scored 20 points and grabbed eight rebounds to lead Northern Michigan.
Indiana guard James Blackmon Jr., who averaged 15.8 points in 13 games before being injured last season, has withdrawn from the NBA draft.
Isaiah Briscoe has decided to withdraw from the NBA draft and will return to Kentucky for his sophomore season. Marcus Lee intends to transfer.
The Big 12/SEC Challenge will again feature Kansas and Kentucky, this time at Rupp Arena. That's not the only exciting matchup in next season's midseason conference showdown.