Nicholas and Bailey had key jumpers down the stretch for the Pilots (3-3) after the Pioneers trailed by just two, 71-69, with 2:17 remaining. Nicholas' two free throws clinched the game, making it 77-70 with 17 seconds to play.
In a game with eight lead changes and five ties, the Pilots' seven-point cushion in the second half was the largest for either team.
Both teams made half their attempts from the floor, with Portland shooting 29 of 57, Lewis & Clark 27 of 54. While the Pilots enjoyed a 34-16 scoring advantage in the paint, the Pioneers made 14 of 26 shots from 3-point range.
Derrick Rodgers added 11 points for Portland.
Oregon could lose multiple players to the NBA next spring, so the Ducks are preparing by pursuing plenty of scorers and an elite frontcourt prospect.
Most of the first-round picks in the 2017 NBA draft haven't played a minute in a college game. Our recruiting experts identify the names to know.
Who are the best NBA prospects in the 2017 draft class? Chad Ford gives his top five and previews the big storylines to watch for next year.