The Panthers (4-3) took the lead for good on a dunk by Corey Law that made it 7-5, stretched the margin to 43-26 at halftime and opened the second half with an 18-0 run that included nine points by Edwards.
Johnson & Wales (3-11), a U.S. Collegiate Athletic Association team, scored just 10 points in the second half, making 4 of 31 shots (12.9 percent). The 63-point margin of defeat matched the Wildcats' most lopsided this season, a 109-46 loss to North Carolina Central on Nov. 12.
Maryland point guard Melo Trimble, considered a lock to leave the program before struggling in the second half last season, has withdrawn from the NBA draft and will return for his junior season.
Louisville's Chinanu Onuaku, who recently underwent a medical procedure to correct a heart rhythm issue detected during the combine, will keep his name in the NBA draft pool.
Andrew White III will return to the Nebraska men's basketball team next season after removing his name from the NBA draft.