Trailing 34-33 early in the second half, Delaware (3-6) went on a 16-3 run, capped by Saddler's 3-pointer to give Delaware a 49-37 lead with 11:25 left to play.
Radford (5-4) struggled shooting in the second half, shooting 29 percent (9 for 31) in the second half compared to Delaware's 46.2 percent (12 for 26).
Radford cut the lead to six, 56-50 with 7:39 remaining, but free throws by Kyle Anderson and a layup by Carl Baptiste pushed the lead back to double figures. Late free throws by Saddler sealed the victory.
Maryland point guard Melo Trimble has withdrawn from the NBA draft and will return to College Park for his junior season, sources told ESPN.
Louisville's Chinanu Onuaku, who recently underwent a medical procedure to correct a heart rhythm issue detected during the combine, will keep his name in the NBA draft pool.
Andrew White III will return to the Nebraska men's basketball team next season after removing his name from the NBA draft.