St. Francis (2-4) played catch up all game long, and pulled within 70-69 following Ben Mockford's 3-pointer with 33 seconds to play, but the Great Danes (7-2) hit 7 of 8 free throws after to earn the win.
Albany, which is now 5-0 all-time against the Terriers, opened with an 18-0 run that spanned over 10 minutes.
The Terriers pulled within 25-22 on Dre Calloway's layup with 4:37 left, but went into another lull and entered halftime down 35-26.
The Terriers tied the game at 41-all on Kevin Douglas' layup with 16:12 left in the second half, but never took the lead.
Travis Nichols led the Terriers with 21 points on 8-of-12 shooting, while Mockford hit six 3-pointers for 18 points.
Maryland point guard Melo Trimble has withdrawn from the NBA draft and will return to College Park for his junior season, sources told ESPN.
Louisville's Chinanu Onuaku, who recently underwent a medical procedure to correct a heart rhythm issue detected during the combine, will keep his name in the NBA draft pool.
Andrew White III will return to the Nebraska men's basketball team next season after removing his name from the NBA draft.