Willie Clayton finished with 10 points and nine rebounds to help Charlotte (9-0) win its ninth consecutive game.
After Kyle Randall's layup cut Central Michigan's (4-4) deficit to two, 34-32, early in the second half, Charlotte outscored the Chippewas 14-3 over the next five minutes to push the lead to 48-35 with 12:10 left to play. Mayfield and Ingram combined for 10 points during the run.
John Simon's layup at the 6:25 mark cut Charlotte's lead to seven, 57-50, but Ivan Benkovic answered with a 3-pointer for the 49ers to push the lead back to double figures. Central Michigan would not get any closer.
Randall scored 15 points to lead Central Michigan while Simon and Olivier Mbaigoto finished with 13 points apiece.
Former Kentucky guard Ed Davender, the only Wildcat with at least 1,500 points and 400 assists, has died. He was 49.
Guard Naz Mitrou-Long, whose 2015-16 season ended in December due to hip problems, has been granted a hardship waiver for the coming season, Iowa State said.
As the Sooners look to life without superstar Buddy Hield and his sidekicks, it's clear their unseasoned players will need to grow up fast.
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