Brandon Young scored 13 points and Melvin finished with 11 points and three blocks in a game where DePaul led by as many as 41. The Panthers beat the Blue Demons last season.
The Blue Demons held Milwaukee to 25.8 percent shooting and forced 17 turnovers.
SMU has signed a second player from Australia, 6-foot-11 forward Harry Froling, to a national letter of intent. The Mustangs previously signed guard Tom Wilson from Australia.
There's nothing to suggest the Jayhawks won't end up atop the Big 12 for a 13th season in a row. But what about a return to the Final Four?
Colorado State graduate transfer John Gillon has chosen Syracuse, giving the Orange a potential starter at point guard entering the 2016-17 season.