O'Neale was 5 of 7 from the field, while Griffin was 3 of 5 and had four rebounds.
Southern Utah had a one point lead early in the first half, but Denver (4-6) led 40-20 at halftime and never looked back. The Pioneers shot 55 percent from the field for the game, while the Thunderbirds shot 40.8 percent.
This was the third-straight home win for the Pioneers.
SMU has signed a second player from Australia, 6-foot-11 forward Harry Froling, to a national letter of intent. The Mustangs previously signed guard Tom Wilson from Australia.
There's nothing to suggest the Jayhawks won't end up atop the Big 12 for a 13th season in a row. But what about a return to the Final Four?
Colorado State graduate transfer John Gillon has chosen Syracuse, giving the Orange a potential starter at point guard entering the 2016-17 season.