Miami took the lead for good with a 16-2 run midway through the second half. Larkin keyed the surge with consecutive 3-pointers. The second of those, with 8:32 remaining, gave the Hurricanes (9-3) their first double-digit lead at 57-47.
Erik Swoope's basket with 7:02 remaining ended the spurt and increased Miami's lead to 61-47.
Tyrone Garland's layup with 6:46 left ended a scoring drought of 3:40 for the Explorers. Garland scored a game-high 20 points to lead LaSalle (9-3).
Scott and Larkin combined to score 26 points in the second half.
Trey McKinney Jones and Kenny Kadji finished with 14 points each for the Hurricanes, who snapped a two-game losing streak. Miami lost the final two games of the Diamond Head Classic in Hawaii against Arizona and Indiana State on Dec. 24 and 25.
The loss snapped a three-game winning streak for La Salle, which was attempting to start a season at 10-2 for the first time since 1989-90.
The Hurricanes rallied from a six-point deficit at halftime and outscored the Explorers 10-2 in the first 3:15 of the second half. Scott's layup with 16:55 remaining ended the early second-half spurt and gave Miami a 40-38 lead.
The Explorers broke open a close first half with a 12-0 run during a late 2:17 stretch. Ramon Galloway hit two 3-pointers and Garland converted three short jumpers during the surge. Garland's basket with 2:03 remaining in the half ended the run and gave the Explorers a 36-25 lead.
Miami cut the lead to 36-30 at halftime on Julian Gamble's layup and Larkin's 3-point play.
La Salle made 6 of 13 3-pointers in the first half but managed only 1 of 8 behind the arc in the second half. Galloway also was held scoreless as he missed all four of his attempts.
Hal "King" Lear, a Temple basketball star during the 1950s, died Saturday at his White Plains, New York home.
Sebastien Bellin's friend Chris Young joins Ryan Smith on Outside the Lines to discuss his friend's bravery, courage and strength after surviving the Brussels bombings in March.
Andrew White III is leaving the Nebraska men's basketball team and will play elsewhere for his final college season.