The Sycamores (9-4, 2-0 Missouri Valley) never trailed after 3:43 remained in the first half and held on despite making just 4 of 8 from the free-throw line in the last 34 seconds.
Trailing by three points, Northern Iowa called its final timeout with 6.5 seconds left to set up a final play. But the Panthers (7-7, 0-2) turned the ball over, and Lucas Eitel hit a free throw for Indiana State.
Seth Tuttle had 24 points and 10 rebounds and James Anthony added 12 points for Northern Iowa.
Gant was 8 of 12 from the field with six rebounds.
Delaware has hired Notre Dame assistant Martin Ingelsby as its next men's basketball head coach, sources told ESPN's Jeff Borzello.
Michigan State-Duke in the ACC/Big Ten Challenge will pit two of the best recruiting classes in the nation. Here's a look at all the games.
The ACC/Big Ten Challenge will be highlighted by Duke's tilt with Michigan State and Indiana's showdown with North Carolina.