John Florveus pulled down 10 rebounds to help the Bulldogs (6-7) overcome a season-high 25 turnovers.
Kevin Larsen scored 14 points to lead George Washington (6-7). The Colonials went 0-for-12 on 3-point attempts, missing all but two of them in the second half.
George Washington shot a season-worst 24.6 percent from the field.
The Bulldogs were just 4-for-11 on free-throw attempts before Caldwell-Pope and Djurisic combined to hit Georgia's last six.
With a trio a top recruits from Philadelphia, the Penn State basketball program is primed to finally turn a corner.
Maryland point guard Melo Trimble, considered a lock to leave the program before struggling in the second half last season, has withdrawn from the NBA draft and will return for his junior season.
Louisville's Chinanu Onuaku, who recently underwent a medical procedure to correct a heart rhythm issue detected during the combine, will keep his name in the NBA draft pool.