Brian Barbour finished with 11 points and a game-high two steals for the Lions (8-5), who have won three straight games. Cisco also pitched in with eight points.
Columbia overcame a five-point, halftime deficit with an improved shooting effort. After shooting 31.8 percent (7 of 22) from the floor in the first half, the Lions made 57.1 percent (16 of 28) of their shots in the second half.
Columbia went on a 9-0 run that was capped by Cory Osetkowski's layup to give it a 43-35 lead with 12:11 left. Cisco scored on a layup with 4:07 remaining to give the Lions a 58-43 advantage -- their largest of the contest.
Mississippi State freshman guard Malik Newman will withdraw from the NBA draft, but sources told ESPN he might explore other opportunities besides returning to Mississippi State.
Seton Hall sophomore Isaiah Whitehead will stay in the NBA draft and not return for his junior season.
Washington State's trio of Josh Hawkinson, Conor Clifford and Ike Iroegbu have withdrawn from the NBA draft and will play their senior season with the Cougars.