Tyrone Garland added 15 points and Jerrell Wright posted a double-double with 10 points and 11 rebounds for the Explorers (10-3), who are now 2-0 this season against Big 5 foes. La Salle also beat Villanova 77-74 in overtime on Nov. 25.
Leading 17-16, the Explorers launched a 15-2 run, with Garland hitting three 3-pointers and scoring 11 points in the spurt.
La Salle, which led by as many as 24 in the second half, hit 9 of 22 from long range in its final game before starting Atlantic 10 Conference play.
ESPN's Dan Dakich joins The Paul Finebaum Show to discuss the SEC's presence in the NBA Draft.
Ted Kapita was the top-rated recruit from West Virginia in the class of 2015 and recently played at DME Academy in Florida.
With the Suns drafting Tyler Ulis, they now have five guards on their roster who attended Kentucky.