Saddler, the league's leading scorer at 19.8 points per game, scored 23 on 9-of-14 shooting, while Threatt had 19 points, made 7 of 13 shots and came up with six steals. Kyle Anderson added 11 points.
The Blue Hens (7-8, 2-0) pulled away with a 16-3 run early in the second half that gave them a 47-33 lead with 13:25 remaining, and they never led by fewer than 11 points the rest of the way.
Daquan Brown came off the bench to score 13 points for the Pride (4-11, 1-1), the only Hofstra player to score in double figures.
Stephen Nwaukoni had 11 rebounds for Hofstra, which beat Georgia State 52-50 Monday night to end an eight-game losing streak.
The family of former Houston Astros owner Roy Hofheinz wants a court to require the University of Houston to keep his name on the school's basketball arena.
Michigan has hired assistant basketball coaches Billy Donlon and Saddi Washington.
Duke and Cincinnati, 2016 NCAA tournament teams, highlight the eight-team field for the Naismith Memorial Basketball Hall of Fame Tip-Off Tournament.