Columbia separated itself from Cornell in the second half, using an 11-0 run that was capped by Cisco's jumper to give the Lions a 55-43 lead with 7:38 left. Cisco, who went 7 of 15 from the floor in the game, scored six points during the spurt.
The Big Red (8-10, 0-1), who had their two-game winning streak snapped, pulled no closer than eight points the rest of way.
Mississippi State freshman guard Malik Newman will withdraw from the NBA draft, but sources told ESPN he might explore other opportunities besides returning to Mississippi State.
Seton Hall sophomore Isaiah Whitehead will stay in the NBA draft and not return for his junior season.
Washington State's trio of Josh Hawkinson, Conor Clifford and Ike Iroegbu have withdrawn from the NBA draft and will play their senior season with the Cougars.