Anthony D'Orazio added 12 points and eight rebounds to help Lehigh (13-4, 3-0) win its fourth straight game.
The Mountain Hawks scored the first nine points of the game, and held Colgate to just 35.7 percent (10 of 28) in the first half to take a 39-26 lead into halftime.
Colgate (6-13, 0-3) trailed the entire game. The Raiders never got within single digits in the second half as the Mountain Hawks led by as many as 17 points in the period.
Though both teams shot poorly in the second half, Lehigh held a 14-3 edge from the free-throw line after the break.
Brandon James led Colgate with 12 points and eight rebounds, but was the only player in double figures.
Mike Krzyzewski says he has good reason to be excited for next season thanks to a combination of Duke's incoming freshmen and a core of experienced upperclassmen.
Georgia guard Juwan Parker has been awarded a medical redshirt, leaving him with two years of eligibility, after missing the 2015-16 season with a partially torn Achilles tendon.
Forward Trevon Bluiett has withdrawn from consideration from the NBA draft and will return to Xavier for his junior season.