Illinois (15-5, 2-4 Big Ten) held Nebraska without a field goal for the last 8:51 of the first half and led 35-23 at the break. The Huskers got no closer than six points the rest of the way.
John Groce, in his first year at Illinois, recorded his 100th win in five seasons as a head coach.
The Illini shot 45 percent and committed 14 turnovers, but they had more offensive rebounds (12) than Nebraska had total rebounds (10) in the first half and finished with a 40-28 advantage on the boards.
Nebraska was 2 of 14 on 3s and shot 32 percent for the game.