Levesque had 15 points on 7 for 7 shooting in the first half, helping Saint Mary's take a 49-40 lead at the break. The Gaels shot 65 percent and had just three turnovers in the opening half, then stretched their lead to as many as 19 points in the second half.
Saint Mary's has beaten Pepperdine 12 straight times, and has won 18 of the last 19 games in the series.
Maryland point guard Melo Trimble, considered a lock to leave the program before struggling in the second half last season, has withdrawn from the NBA draft and will return for his junior season.
Louisville's Chinanu Onuaku, who recently underwent a medical procedure to correct a heart rhythm issue detected during the combine, will keep his name in the NBA draft pool.
Andrew White III will return to the Nebraska men's basketball team next season after removing his name from the NBA draft.