Reggie Spencer scored 14 points and Dinko Marshavelski added 11 points for the Huskies (13-7, 8-0), who have won eight in a row and nine of their last 10. One of those wins was at George Mason on Jan. 3, 84-74.
Northeastern is off to its best start in CAA play since becoming a member in 2005.
The Huskies, coming off a double-overtime win Wednesday night over William & Mary, shot 57 percent in the second half and 53 percent for the game.
Vertrail Vaughns scored 13 points and Sherrod Wright scored 12 to lead the Patriots (12-8, 5-3), whose three-game winning streak ended. George Mason fell into a second-place tie with James Madison in the CAA.
ESPN's Dan Dakich joins The Paul Finebaum Show to discuss the SEC's presence in the NBA Draft.
Ted Kapita was the top-rated recruit from West Virginia in the class of 2015 and recently played at DME Academy in Florida.
With the Suns drafting Tyler Ulis, they now have five guards on their roster who attended Kentucky.