Purdue never trailed in overtime. Ronnie Johnson scored the go-ahead basket with 1:27 left in overtime to give Purdue a 61-59 lead. The Hawkeyes missed two free throws and two field goals and Byrd extended the lead with two free throws with 30 seconds left to make it 63-59.
The two teams meet again on Feb. 27 in Iowa City.
Authorities say former Michigan State basketball player Keith Appling has been charged with carrying a concealed weapon and other crimes.
Point guard Jaylen Fisher, who reopened his recruitment after coaching changes at UNLV, has committed to TCU over a long list of schools.
Forward Kennedy Meeks, who has averaged 9.4 points and 6.5 rebounds at North Carolina, has pulled out of the NBA draft and will return to the Tar Heels.