The Crusaders (17-6, 7-2 Horizon), who had won six in a row before losing Wednesday night at Youngstown State, led by as many as 36 points in Friday's game. Valparaiso led 37-21 at halftime in running its home record to 11-1.
Jordan Aaron led Milwaukee (5-18, 1-8) with 17 points. The Panthers fell behind to stay 5 minutes into the game in dropping their fifth in a row, and they are 0-11 on the road this season.
Florida State's student government has passed a resolution discouraging Seminoles fans from wearing Native American headdresses at games.
The second annual Gavitt Tipoff Games, eight games between members of the Big East and Big Ten to be played Nov. 14-18, will feature Villanova at Purdue in the opener.
Michael Lewis is leaving his assistant coaching job at Butler to take the same position at Nebraska under Tim Miles.