The Crusaders (17-6, 7-2 Horizon), who had won six in a row before losing Wednesday night at Youngstown State, led by as many as 36 points in Friday's game. Valparaiso led 37-21 at halftime in running its home record to 11-1.
Jordan Aaron led Milwaukee (5-18, 1-8) with 17 points. The Panthers fell behind to stay 5 minutes into the game in dropping their fifth in a row, and they are 0-11 on the road this season.
Washington State's trio of Josh Hawkinson, Conor Clifford and Ike Iroegbu have withdrawn from the NBA draft and will play their senior season with the Cougars.
Gonzaga center Przemek Karnowski, who missed most of last season with a back injury, says he is returning for another year.
Wisconsin forward Nigel Hayes has withdrawn from the NBA draft and will return to the Badgers for his senior season.