Sam Mills and Jerrell Wright had 12 each, with Wright grabbing eight rebounds. Tyreek Duren and Tyrone Garland scored 11 apiece for La Salle (15-6, 5-3 Atlantic 10 Conference). Duren passed Larry Cannon for 15th place on the Explorers' all-time assists list with 352 and tied Shawn Smith for 10th on the career steals list with 165.
Isaiah Armwood led George Washington (10-10, 4-3) with 17 points and nine rebounds, Patricio Garino and Dwayne Smith had 11 each and Kevin Larsen chipped in 10. The Colonials had won three straight A-10 games coming in.
The Explorers knocked down 11 of 25 from beyond the arc to the Colonials' 3 of 11, and La Salle scored 24 points off turnovers to George Washington's six.
Dillon Brooks, who led Oregon with 16.7 points per game last season, will opt out of the NBA draft process and return to the Ducks, a source told ESPN.
Mississippi State freshman guard Malik Newman will withdraw from the NBA draft, but sources told ESPN he might explore other opportunities besides returning to Mississippi State.
Seton Hall sophomore Isaiah Whitehead will stay in the NBA draft and not return for his junior season.