Detroit (16-8, 8-3 Horizon) shot 52.5 percent from the field and was 13 of 16 from the free-throw line but the Titans watched Milwaukee drain 10 3-pointers and outscore their bench 32-4.
Tied at 46, Ryan Haggerty hit a 3-pointer to put the Panthers on top 49-46 with 13:14 remaining in the game. Detroit regained the lead after a Ray McCallum fast break dunk to make it 50-49 and the Titans never trailed again.
James Haarsma had 26 points on 9-of-13 shooting including a perfect 7 for 7 from the line to lead Milwaukee (5-19, 1-9).
Doug Anderson and McCallum finished the night with 16 points apiece for Detroit, which has won four straight.