The Salukis (11-15, 4-11 Missouri Valley), who snapped a seven-game losing streak in the series, scored the game's first 10 points, never trailed and shot 51.2 percent (22 of 43) from the floor.
Missouri State trailed by nine points at intermission but got within 40-38 midway through the second half. But the Bears then went scoreless for a stretch of 6:01, enabling Southern Illinois to take permanent control.
Anthony Beane scored five points and T.J. Lindsay hit a 3-pointer during a 10-0 run. Beane's three-point play made the score 50-38 with five minutes remaining, and Missouri State got no closer than six points the rest of the way.
High school junior Zach Brown, a 7-footer from Miami, has rescinded his commitment to UConn, sources told ESPN.
Reserve center Akolda Manyang has been charged with felony aggravated assault after being accused of punching a man in the face without provocation.
Should the 76ers take Ben Simmons No. 1? What if they get the Lakers' pick, too? And how does the rest of the top 10 shake out? Our Insiders run their latest mock draft, with Philly on the clock.