The two guards each made 4 of 7 from 3-point range. The Terriers (16-11, 10-4 America East Conference), who have won five straight, made 10 of 25 behind the arc to 3 of 15 for the Great Danes (19-9, 8-6).
Papale started the second half with a pair of jumpers to increase a 32-30 halftime lead to six points. Maurice Watson Jr. followed with two more baskets for a 40-30 lead.
Albany got within five points on several occasions, but layups by Watson and Dom Morris made it 66-57 with 4:04 remaining.
Morris finished with 16 points and nine rebounds, and Watson had 11 points and 10 assists.
Bruce Weber's Kansas State team earned a share of the Big 12 title three years ago, but a lot has changed since then and the pressure is on.
NCAA title game hero Kris Jenkins said he will withdraw his name from the NBA draft and return to Villanova for his senior season.
Andy Katz breaks down the likelihood of Villanova, Syracuse, North Carolina or Oklahoma making a run to the Final Four next season.