Sykes hit 6 of 13 from the field and 10 of 15 at the foul line and added seven rebounds. Spurlock also grabbed seven boards and added a 4-of-7 showing from 3-point range for the Knights (18-9, 8-5).
Tulsa (14-13, 6-7) led 38-35 shortly after halftime, but the Knights used a 7-0 run to take the lead. The Golden Hurricane pulled within 48-45 with 12:36 left, but then Sykes' layup sparked a 12-2 run to build an insurmountable cushion.
Andrew White III will return to the Nebraska men's basketball team next season after removing his name from the NBA draft.
Mike Brey is looking at former Notre Dame players to fill two assistant jobs that have opened up with the departures of Martin Ingelsby and Anthony Solomon.
Purdue's 2016-17 prospects got a jolt Wednesday when forward Caleb Swanigan announced he will return for his sophomore season.