Saunders shot 7-of-9 from the field while Moundou-Missi was 10-of-15 and led the Crimson (4-0) with nine rebounds. Harvard shot 57.1 percent from the field.
Dyami Starks came into the game for Bryant (2-2) as the nation's leading scorer with 100 points through three games, but was held by Harvard to just 11 points.
Bryant trailed by 8 with nine minutes to play but Harvard went on a 13-2 run to extend its lead to 76-57.
Bryant shot just 2-of-13 from behind the 3-point arc and had 11 shots blocked by the Crimson. Alex Francis led the Bulldogs with 17 points.
Andy Katz breaks down the likelihood of Villanova, Syracuse, North Carolina or Oklahoma making a run to the Final Four next season.
Florida State has announced that Xavier Rathan-Mayes will return to the court for his junior season. The 6-foot-4 guard declared for the NBA draft last month but did not hire an agent.
Virginia coach Tony Bennett takes the ACC Fast Break with Dino Gaudio by answering questions like who the best Tony Bennett is and what other sport he'd like to coach.