Saunders shot 7-of-9 from the field while Moundou-Missi was 10-of-15 and led the Crimson (4-0) with nine rebounds. Harvard shot 57.1 percent from the field.
Dyami Starks came into the game for Bryant (2-2) as the nation's leading scorer with 100 points through three games, but was held by Harvard to just 11 points.
Bryant trailed by 8 with nine minutes to play but Harvard went on a 13-2 run to extend its lead to 76-57.
Bryant shot just 2-of-13 from behind the 3-point arc and had 11 shots blocked by the Crimson. Alex Francis led the Bulldogs with 17 points.
Mike Brey is looking at former Notre Dame players to fill two assistant jobs that have opened up with the departures of Martin Ingelsby and Anthony Solomon.
Purdue's 2016-17 prospects got a jolt Wednesday when forward Caleb Swanigan announced he will return for his sophomore season.
Clemson's Jaron Blossomgame says he is withdrawing from the NBA draft and returning to school for a final season.