Saunders shot 7-of-9 from the field while Moundou-Missi was 10-of-15 and led the Crimson (4-0) with nine rebounds. Harvard shot 57.1 percent from the field.
Dyami Starks came into the game for Bryant (2-2) as the nation's leading scorer with 100 points through three games, but was held by Harvard to just 11 points.
Bryant trailed by 8 with nine minutes to play but Harvard went on a 13-2 run to extend its lead to 76-57.
Bryant shot just 2-of-13 from behind the 3-point arc and had 11 shots blocked by the Crimson. Alex Francis led the Bulldogs with 17 points.
Jalen Rose and David Jacoby announce their choices for sleepers in the 2016 NBA Draft.
Daryl Gross, who spent a decade as Syracuse's athletic director, will start as Division II Cal State-Los Angeles' AD in July.
Utah forward Brekkott Chapman, who averaged 4.4 points and 2.8 rebounds last season, has transferred to Weber State, coach Randy Rahe announced Wednesday.