Upshaw hit two from the line and Jamall Robinson added another two free throws following a Newmen turnover. Malcom McMillan made a layup to pull the Blue Devils (3-7) within three with eight seconds remaining, but couldn't connect on a 3-pointer following an Upshaw free throw.
Four of the seven players that saw action for Hofstra scored in double figures, as Kone and Robinson each had 13.
Maryland point guard Melo Trimble, considered a lock to leave the program before struggling in the second half last season, has withdrawn from the NBA draft and will return for his junior season.
Louisville's Chinanu Onuaku, who recently underwent a medical procedure to correct a heart rhythm issue detected during the combine, will keep his name in the NBA draft pool.
Andrew White III will return to the Nebraska men's basketball team next season after removing his name from the NBA draft.