The Colonels (8-4) were up 44-26 at halftime after shooting 63 percent. The Aggies (3-8) committed 14 turnovers in that half, which the Colonels, third in the nation in steals, turned into 24 points.
The Aggies suffered from poor 3-point shooting, making 3 of 15 attempts. They still managed to get within eight points twice in the second half, including with 1:48 left, but a 3-pointer and free throw by Lewis put the game out reach.
The Colonels were outrebounded 36-18 but overcame that with the help of 46.4 percent 3-point shooting (13 of 28).
EKU tied a program record with its 21st straight home nonconference victory.