OMAHA, Neb. -- St. John's dared Doug McDermott to beat the Red Storm. He did.
McDermott hit a falling-away, 25-footer with 2.5 seconds left to finish his season-high 39-point night, and No. 20 Creighton won 63-60 after squandering all of an 18-point lead Tuesday.
It was the second time this season McDermott won a game in the last seconds. He did it against Saint Joseph's in November.
"At home this is the best feeling I've ever had," McDermott said. "That Saint Joe's one was pretty good, too. This tops it."
The two-time returning All-America carried his team to its 13th win in 14 games, keeping the Bluejays (18-3, 8-1) in first place in the Big East. St. John's (12-9, 2-6), playing in Omaha for the first time since 1966, had its three-game winning streak end.
McDermott bounced back from a tough shooting game in a win over Georgetown on Saturday to turn in one of his greatest all-around performances.
The Red Storm had just tied the game on Rysheed Jordan's two free throws before McDermott took a pass from Jahenns Manigat on the left wing. Isaiah Zierden set a screen for McDermott, and he got off his fade-away 3-pointer just as shot-blocking specialist Chris Obekpa broke through to wave a hand in his face.
"Big-time shot by a big-time player," St. John's coach Steve Lavin said.
The Red Storm had a last chance to tie, but Phil Greene IV's shot at the buzzer didn't even touch the net.
It was a fitting end for McDermott, whose monster game offset an otherwise poor offensive showing by the Bluejays.
St. John's defensive strategy was to take away all the complementary pieces of Creighton's offense.
"We have the best player in America as a great counter for that," Manigat said.
In particular, the Red Storm took away Ethan Wragge, who tied a school record with nine 3-pointers in a 28-point win over Villanova last week.
"Last week was Ethan Wragge Week across the country," Creighton coach Greg McDermott said, "so I would certainly think about doing the same thing, especially if you have the length and athletic ability that coach Lavin has. Doug hit some tough shots. As a defense, that's what you're after."
McDermott was making a lot of those tough shots and had his seventh 30-point game of the season. He finished 15 of 26 from the field, including 5 of 9 on 3s. He had six rebounds, including a couple of big ones late.
The rest of the Bluejays shot 8 of 21 from the field, and the team committed 17 turnovers that St. John's converted into 21 points. The Red Storm outscored Creighton 18-0 on fast breaks.
"If you had told me we would be outscored 21-4 on points off turnovers and 18-0 on fast breaks," Greg McDermott said, "I wouldn't have thought we would have been sitting here talking about a victory."
D'Angelo Harrison scored 13 of his 15 points in the second half to lead St. John's. Obekpa and Jordan had 11 apiece and JaKarr Sampson added 10.
Creighton led by 18 points with 12 minutes to play, but the Red Storm came back with runs of 11-2 and 12-2. Sampson tied it 58-all, but McDermott answered with a left-handed floater.
Austin Chatman fouled Jordan with 11.1 seconds left, and the freshman made both free throws to set up McDermott's dramatic shot.
"I'm proud of the fight and resiliency we showed coming back from 18 down," Lavin said. "That was impressive, but not enough to get over the hump. That's because we buried ourselves earlier in the game."
McDermott scored every way imaginable, from in close to well beyond the 3-point line.
He flashed a baby hook along the baseline and even led a fast break, only to have the ball stripped as he went down hard, drawing a round of boos at CenturyLink Center. He grimaced as he got up but stayed in the game.
Wragge had difficulty getting open all night. Orlando Sanchez, Sampson and others took turns denying him the ball, and the Red Storm did a good job switching defenders when the Bluejays tried to set up a screen.
Wragge's first 3-pointer came just over 5 minutes into the second half, and that was after he broke free from Sampson, who had grabbed a handful of his jersey.
"There aren't a bunch of nights like this, not where I shoot 26 shots," Doug McDermott said. "They took a lot of our shooters and made it hard to get them openings. My teammates told me to keep shooting. Who knows? Next game I could shoot 10 times."
Maryland point guard Melo Trimble has withdrawn from the NBA draft and will return to College Park for his junior season, sources told ESPN.
Louisville's Chinanu Onuaku, who recently underwent a medical procedure to correct a heart rhythm issue detected during the combine, will keep his name in the NBA draft pool.
Andrew White III will return to the Nebraska men's basketball team next season after removing his name from the NBA draft.