The Pilots (11-7, 3-3 West Coast Conference) shot 47.1 percent from the field. Kevin Bailey scored 13 points and Thomas Van Der Mars chipped in 10 with eight boards.
Portland held a 36-29 advantage at halftime, but trailed by two after Loyola Marymount (10-9, 2-5) opened the second half on an 11-2 run. Sharp responded, hitting three of his four 3-pointers to spark a 20-4 run and make it 58-44 with 8:50 remaining.
The Pilots have won three of their last four games, including an 82-73 upset of No. 22 Gonzaga on Jan. 9.
NCAA title game hero Kris Jenkins said he will withdraw his name from the NBA draft and return to Villanova for his senior season.
Andy Katz breaks down the likelihood of Villanova, Syracuse, North Carolina or Oklahoma making a run to the Final Four next season.
Florida State has announced that Xavier Rathan-Mayes will return to the court for his junior season. The 6-foot-4 guard declared for the NBA draft last month but did not hire an agent.