(12) Ohio State 45, 
(20) Michigan State 7
3:30 PM ET, October 18, 2008
Spartan Stadium
EAST LANSING, MI
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College Football Scores
Other Scores:
Thursday, October 16th
| 9 Brigham Young | 7 | Final |
| TCU | 32 |
Friday, October 17th
| Hawaii | 7 | Final |
| 15 Boise State | 27 |
Saturday, October 18th
| 11 Missouri | 31 | Final |
| 1 Texas | 56 |
| Mississippi | 20 | Final |
| 2 Alabama | 24 |
| Michigan | 17 | Final |
| 3 Penn State | 46 |
| 16 Kansas | 31 | Final |
| 4 Oklahoma | 45 |
| 6 USC | 69 | Final |
| Washington State | 0 |
| 7 Texas Tech | 43 | Final |
| Texas A&M | 25 |
| Baylor | 6 | Final |
| 8 Oklahoma State | 34 |
| 22 Vanderbilt | 14 | Final |
| 10 Georgia | 24 |
| 12 Ohio State | 45 | Final |
| 20 Michigan State | 7 |
| 13 LSU | 24 | Final |
| South Carolina | 17 |
| Colorado State | 16 | Final |
| 14 Utah | 49 |
| 17 Virginia Tech | 23 | Final |
| Boston College | 28 |
| 18 North Carolina | 13 | Final |
| Virginia | 16 | OT |
| Syracuse | 13 | Final |
| 19 South Florida | 45 |
| 21 Wake Forest | 0 | Final |
| Maryland | 26 |
| 23 Pittsburgh | 42 | Final |
| Navy | 21 |
| 25 California | 27 | Final |
| Arizona | 42 |