Griffin completed 21 of 34 for 314 yards and three touchdowns for the Green Wave (4-6, 2-4 Conference USA). Grant also caught a 40-yard touchdown from running back Orleans Darkwa, who carried 26 times for 113 yards and threw a 3-yard touchdown pass to Cody Sparks on his only other attempt.
The Owls (2-8, 1-5), trailing 38-21 at halftime, replaced Nick Fanuzzi, who had thrown three interceptions, with Taylor Cook. Cook directed Rice to four touchdowns, including a 29-yard pass to Patrick Randolph with 2:02 remaining.
After Tulane regained the lead on Griffin's pass to Grant, Rice drove to a first down at the Green Wave 14. After two plays gained 3 yards, two incompletions turned the ball over on downs.
Steve Spurrier, the visor-slinging, slick-talking "Head Ball Coach" who is the second-winningest coach in Southeastern Conference history, announce his resignation on Tuesday.
Steve Sarkisian has been plagued of late by apparent substance-related circumstances, including arriving to team facilities appearing intoxicated Sunday, according to sources.
Florida Gators quarterback Will Grier has been suspended for the year after testing positive for a performance-enhancing substance found in a supplement, coach Jim McElwain announced Monday.
Former NFL safety Tyler Sash died from an accidental overdose after mixing two powerful pain medications, and a history of injuries was a contributing factor, a medical examiner said.
Former USC coach Pete Carroll said Monday that he's saddened by Steve Sarkisian's situation and he has reached out to his former assistant.
Ole Miss offensive tackle Laremy Tunsil will be eligible to return to action for the Rebels following Saturday's game against Memphis, sources told ESPN.com on Monday.