Walker, a senior, suffered a fractured spine when he collided with teammate Julius Warmsley, a defensive lineman, helmet-to-helmet while attempting to make a tackle. Walker was unable to move and was taken off the field in an ambulance and transported to a Tulsa hospital.
Walker was in stable condition and will need spinal surgery in the "the next day or two," said Tulane's team doctor, Buddy Savoie.
"He was stable when we transported him," Savoie said. "I do not think, based on the information we have, his life was ever in danger."
The injury happened on the final play of the first half.
Cody Green threw for 274 yards and two scores, including a 74-yarder to Thomas Roberson, as the Golden Hurricane (1-1) raced to a 35-3 halftime lead. Tulsa outgained Tulane (0-2) in rushing yards, 364-7.
The Spartans' offensive line gains experience with the return of Brandon Clemons, who has played in every game the past two seasons.
Paul Finebaum shares his thoughts on the great quality of coaches in the SEC.
GameDay 100: Oregon thought they had Michael Dyer down, but he just kept on running.
This week's mailbag takes a look at the obvious and the dark horse breakout candidates this season in the Big 12.
Brenda Tracy, who was allegedly raped at Oregon State in 1998, will meet Wednesday with former Beavers coach Mike Riley, who now coaches at Nebraska.
Oregon will need more from its defense, but it's an inexperienced group that still has a lot to prove.