Keeton completed 20 of 33 passes and Williams ran for 113 yards on 20 carries and caught seven passes for 147 yards for the Aggies, who are 4-1 for the first time since 1978. On the first play from scrimmage in the fourth quarter, Keeton hit Williams for a 74-yard touchdown pass to give Utah State a 27-13 lead.
Nick Sherry completed only 18 of 39 passes for 188 yards for the Rebels (1-4). His 3-yard scoring pass to Max Johnson in the second quarter was the first touchdown allowed by the Aggies in the first half this season.
Keeton was the first Utah State QB to pass for 400 yards since 2002.
Chuck Jacobs caught four passes for 101 yards and two touchdowns for Utah State.
South Carolina has decided to give up Saturday's home game against No. 7 LSU because of devastating floods that have hit the state, moving the game to Baton Rouge.
West Virginia All-Big 12 safety Karl Joseph is out for the remainder of the season after injuring his knee during a non-contact drill in Tuesday's practice.
Rutgers has reinstated senior wide receiver Leonte Carroo a day after an assault charge against him was dropped.
Tennessee senior wide receiver Alton "Pig" Howard has been dismissed from the team for a violation of team rules, coach Butch Jones announced.
UCLA junior linebacker Myles Jack has withdrawn from school and will enter the NFL draft, making the decision just weeks after suffering a season-ending knee injury.
Police charged a former Michigan football player with three felonies Wednesday related to an accusation that he filmed part of a sexual encounter with a woman without her knowledge or consent.